Finding the self by losing the self: neural correlates of ego-dissolution under psilocybin

Record summary

Lebedev and colleagues examined the relationship between reported ego-dissolution during psilocybin experiences and functional brain changes. The lead is valuable for comparing subjective alterations in selfhood with network-level measures, particularly communication among systems associated with self-related processing. It is not evidence that the self literally disappears or that psychedelic reports reveal metaphysical truths. Verification should cover the participant sample, rating instruments, imaging analyses and the distinction between correlation with reported experience and causal explanation.