The effects of psilocybin and MDMA on between-network resting state functional connectivity

Record summary

Roseman and colleagues compared resting-state functional connectivity after psilocybin and MDMA, focusing on communication between normally distinct brain networks. The comparison is useful because the drugs can produce overlapping changes in mood or social experience while differing pharmacologically and phenomenologically. Findings may help separate general arousal or emotional effects from psychedelic-specific network changes. This is a pharmacological fMRI study, not a test of extrasensory perception. Verify the drug conditions, resting-state design, participant characteristics and connectivity statistics.